Indiana Jones (Harrison Ford) and his old friend George "Mac" McHale (Ray Winstone), suddenly find themselves dropped out of trunk and into the arms of Russian agent Irina Spalko (Cate Blanchett). Her goal is to find the missing Crystal Skull as she believes with it comes the greatest of all powers from another world. But Indiana Jones soon find himself pitted against even his old friend Mac, as he has joined up with the wrong side obsessed with the money. Jones makes fast work out of locating the skull in a large storage facility and makes his escape only to be watched by the Russians who still need his help.
Mutt Williams (Shia LaBeouf) an arrogant teenage rowdy boy who is way too much into his looks, is trying to track down Jones as he thinks he can help save his mother from doom as she has been taken hostage. Jones doesn't want to become involved but when the Russians are on to his location, he makes a quick get away with Mutt on his bike. Since it seems Jones can't return home anymore, he decides to help Mutt with his quest.
As the two solve a serious of riddles to get to the crystal skull, they come in contact with Mutt's mother, Marion Ravenwood (Karen Allen) where she is being held. Jones realises now he has a son and together they must escape but not before fulfilling their quest of returning the crystal skull to it's resting place.
Director: Steven Spielberg, George Lucas
Writer: David Koepp
Producer: Frank Marshall